Based on company reports and required federal notifications

1. American Airlines, 550

• Bankrupt airline closed Tucson reservation center; still employs 439 in region, including home-based agents

2. VT Services, 107

• Defense contractor at Fort Huachuca announced layoffs in January

3. Sykes Enterprises Inc., 85

• Nogales call center closed

4. Global Solar Energy, 39

• Has since announced further cuts totaling 70 percent of staff as it seeks new investors

5. Hostess Brands Inc., 43**

• Bankrupt Twinkie maker shut down operations nationwide

**Total layoffs in Southern Arizona reported under federal Workforce Adjustment and Retraining Notification Act