Arizona Daily Star editorial cartoonist David Fitzsimmons is producing a benefit comedy show at Laffs Comedy Caffe on Wednesday, Oct. 11, that features an all-female cast and one man: Dave “Guestosterone” Fitzsimmons.

Hey, shouldn’t the guy doing the heavy lifting be allowed 15 minutes of fame? Exactly!

He’ll join a cast headed by veteran Tucson standup Nancy Stanley, who’s hosting “Titters: The Estrogen Hour’s Finest Hour in Support of Making Strides against Breast Cancer.” Proceeds benefit efforts to raise awareness about and money to treat breast cancer, which Fitzsimmons said “took my mighty mom and my sweet sis.”

Also on the lineup is Boston transplant Amber Frame; Mo Urban, who has hosted comedy and improv shows around Tucson; comedian and breast cancer survivor Stacy Scheff; Tucson comedian, muralist and chalk artist Bridgitte Thum; comedian and improv artist Esther Brilliant; and headliner Traci Skene from Las Vegas, who has appeared on “Last Comic Standing” and penned “Sometimes Ask A Man,” which she will no doubt shamelessly promote. (Available on Amazon.com and for free on Kindle.)

Skene is sticking around Tucson for a few days to appear as the featured comic when her husband Brian McKim, a “Last Comic Standing” semi-finalist who has performed in all 50 states, headlines Laffs on Oct. 13 and 14. Details at laffstucson.com.

Wednesday’s 21-and-old show starts at 7 p.m., doors open at 6. Tickets are $15 in advance by emailing tooner@tucson.com or $20 at the door, 2900 E. Broadway.

Contact reporter Cathalena E. Burch at cburch@tucson.com or 573-4642. On Twitter @Starburch

I cover music for the Arizona Daily Star.