Multiple drug busts over the weekend netted Customs and Border Protection officers nearly $800,000 worth of heroin, methamphetamine and marijuana.

Friday a 36-year-old Yuma man was busted by a drug sniffing dog as he tried to cross into the United states at the San Luis port of entry.

A search of his Toyoda sedan turned up 35 pounds of crystal meth in the doors and rear seats, according to a CBP news release. The meth had a street value of almost $104,000.

Saturday morning at a checkpoint near Why, agents stopped a Saturn sedan for an immigration inspection. Agents became suspicious when “the driver and passenger refused to answer any immigration questions,” the news release stated. “The passengers quickly became uncooperative and very argumentative, a tactic commonly used by smugglers at our interim checkpoints.”

The sedan was directed to a secondary area for further inspection and a narcotics detection dog smelled drugs near the trunk when it was walked around the sedan. A search of the car turned up 126 pounds of marijuana with a street value of about $63,000.

At the Nogales port of entry Saturday, a 27-year-old Mexican man was arrested after officers found meth and heroin in the Kentworth tractor he was driving. The 44 pounds of meth and 25 pounds of heroin were hidden in the smoke stack mufflers. The stash totaled $485,000.

Sunday at the San Luis port of entry, officers searched a 33-year-old Sonora, Mexico, woman who was crossing on foot. They found traces of marijuana in her purse more than 10 pounds of heroin taped to her abdomen. The drugs were valued at more than $141,000.

In all cases, the drugs and vehicles involved were seized and the suspects were turned over to U.S. Immigration and Customs Enforcement’s Homeland Security Investigations.