Officers at Nogales ports of entry seized more than 42 pounds of heroin and 5 pounds of cocaine in two separate incidents on Wednesday.

The drugs are worth an estimated $626,000, according to a news release from U.S. Customs and Border Protection.

At the Mariposa border crossing, officers sent Forrest Frederick Sims, 62, of Tucson, for an additional inspection of his Honda car.

A Border Patrol drug dog alerted to the vehicle’s glove box, where officers found 14 packages of drugs. Twelve packages contained nearly 28 pounds of heroin, worth an estimated $374,000, while the other two contained about 5 pounds of cocaine, worth $46,000, the release said.

Wednesday night, officers at the Dennis DeConcini Port of Entry sent two women from Tucson to a secondary inspection of their Hyundai sedan. A dog alerted to the presence of drugs in three backpacks in the car. Officers found six packages of heroin, weighing about 15 pounds. The heroin is estimated to be worth $206,000, according to the news release.

Officers arrested Summer Knowles, 25, and her passenger in the car, Rosario Ochoa-Rojas, 22.

The vehicles and drugs were seized. All three suspects were referred to U.S. Immigration and Customs Enforcement’s Homeland Security Investigations.