A crash involving a semi-truck and a car closed down a portion of Interstate 10 on Tucson's southeast side early Monday morning.

Mamta Popat / Arizona Daily Star

Traffic is flowing again on Interstate 10 following a deadly wreck early this morning.

A commercial truck tractor pulling a semitrailer was headed west when it crossed the median and began to roll over at 3:42 a.m., according to the Arizona Department of Public Safety.

The truck hit a car in the eastbound lanes. The car burst into flames, and the fire spread to the truck, according to DPS.

The fire was extinguished two hours later, according to DPS. Both drivers died in the crash.

The wreckage has caused major delays since early Monday morning, closing eastbound I-10 at Kolb Road and the westbound lanes at Rita Road for hours.

Westbound lanes were reopened five hours after the crash while eastbound lanes were fully reopened about an hour later.

Go to to www.az511.gov for the most current information about Arizona highway closures and restrictions.