Broncos (6-3) at Panthers (2-6)

11 a.m. • Ch 13 • Line: Broncos by 4

• Peyton Manning is closing in on more milestones, and current coach John Fox would be a very willing recipient of Manning's latest achievements against the team that fired him after the 2010 season. With two touchdown passes at Carolina, Manning would pass Dan Marino for the second-most touchdown passes in NFL annals; Marino had 420. Brett Favre holds the record with 508. And with a win, Manning would tie Marino with 147 career regular-season victories, trailing only John Elway (148) and Favre (186).

Cowboys (3-5) at Eagles (3-5)

2:25 p.m. • Ch 11 • Line: Cowboys by 2

• The Cowboys and Eagles were going to challenge the Giants for NFC East supremacy. Instead, they face off Today in what might be dubbed the Flop Bowl: a pair of 3-5 teams with deep-rooted problems. What once was a matchup of high-profile teams that offered plenty of excitement and big plays, Cowboys-Eagles now looks like a Keystone Cops movie. Or maybe the Three Stooges. Philadelphia has scored a meager 133 points, but Dallas isn't much better with 150. The Eagles displayed their weakness at tackling in last Monday's debacle at New Orleans, and the Cowboys have had similar fundamental problems all year. Both teams are turnover machines, too. Michael Vick can't hold onto the ball, but neither can Dallas' receivers. Vick and the Eagles have 19 giveaways, including an absurd 10 fumbles. The Cowboys also have turned it over 19 times, with Tony Romo leading the NFL with 13 interceptions.

Falcons (8-0) at Saints (3-5)

11 a.m. • Line: Falcons by 2 1/2

• Usually, this is a meeting of NFC South titans, but the Saints have not done their part. Still, they come off their best performance in a 28-13 victory over Philadelphia, their third win in four games. And they surely will be stoked to play the runaway division leaders, especially with the Falcons being undefeated. "For the players, it feels like every time we play the Falcons it's such a big game, whether it be our standings or the meaning of the game (or) just the fact that we're divisional opponents," Saints quarterback Drew Brees said. Eight teams have gone 9-0 since 2002. Four went on to play in the Super Bowl and two (2006 Indianapolis and 2009 New Orleans) won it.

Lions (4-4) at Vikings (5-4)

11 a.m. • Line: Lions by 2 1/2

• Teams headed in opposite directions: Minnesota has lost two in a row and three of four as the passing game has disappeared. The Vikings have a dynamic, multi-dimensional wideout in Percy Harvin, but he probably won't help QB Christian Ponder with his struggles. Harvin is doubtful to play after spraining an ankle last Sunday. He has been sporting a noticeable limp and didn't practice all week. At least they have the league's top rusher, Adrian Peterson, to be a focal point. Lately, the Lions have displayed offensive balance, getting strong performances from someone other than Calvin Johnson. Second-year pros RB Mikel Leshoure and WR Titus Young have been especially effective.

Chargers (4-4) at Buccaneers (4-4)

11 a.m. • Line: Buccaneers by 3

• Vincent Jackson is having a terrific first season with the Buccaneers, and now he gets to show how good he is playing against the team that let him walk as a free agent after several contract hassles. Jackson has 31 catches for 710 yards and six touchdowns, but most eye-opening is his 22.9-yard average per reception - game-breaker territory. No one in the league with as many as 20 catches comes close. "Vincent is a great talent with his size and speed. He also has great hands and the ability to catch the ball in traffic and make things happen," quarterback Josh Freeman said. "Vincent's been tremendous. He complements Mike Williams and vice versa."

Titans (3-6) at Dolphins (4-4)

11 a.m. • Line: Dolphins by 6

• Titans owner Bud Adams put everyone on alert for their jobs after last week's fiasco against Chicago. Most pressing is finding someone - anyone - who can play some defense. Tennessee has allowed 308 points, historically bad numbers, and ranks 30th in overall D. Jake Locker will return at quarterback for the Titans, barring a setback to his left, non-throwing shoulder. He missed five games. Miami hasn't allowed a 100-yard rusher in 22 consecutive games, but Chris Johnson has run for more than 100 yards both times he has faced the Dolphins.

Bills (3-5) at Patriots (5-3)

11 a.m. • Line: Patriots by 13

• The final of the four teams coming back from an idle week, the Patriots have to love the Bills being their first opponent. New England has won 17 of the last 18 against the Bills and scored a season-high 52 points in its win at Buffalo on Sept. 30, with touchdowns on six straight second-half possessions. Buffalo ranks 31st in defense, while the Patriots are No. 1 with 32.8 points and 440.8 yards per game. Brady is 19-2 against the Bills with 49 TD passes.

Raiders (3-5) at Ravens (6-2)

11 a.m. • Line: Ravens by 7 1/2

• The Ravens have won six of the seven meetings and three in a row. Oakland comes in limping, particularly at running back with both Darren McFadden and Mike Goodson dealing with sprained right ankles. Baltimore, which has won 14 consecutive home games, has two players in reach of milestones. Ray Rice needs 1 yard rushing to reach 5,000 for his career.

Jets (3-5) at Seahawks (5-4)

2:05 p.m. • Line: Seahawks by 6

• The Jets are coming off a bye during which they tried to fix, well, everything. In their last outing, they were awful on offense, defense and special teams in a loss to Miami. Of special interest here is the relationship between Seahawks coach Pete Carroll and Jets QB Mark Sanchez. When both were at Southern California, Carroll urged Sanchez to return for his senior year, saying he didn't think Sanchez was ready for the NFL. But Sanchez left - and led the Jets to the AFC title game in his first two seasons after being selected in the first round of the 2009 draft.

Rams (3-5) at 49ers (6-2)

2:25 p.m. • Line: 49ers by 12 1/2

• Both teams come off byes, with the Rams playing their worst game of the season in their "home" contest against New England in London. They have lost seven of the last eight in this series. San Francisco has an 11-game home winning streak against the NFC West. Only Tom Brady has thrown fewer interceptions than Alex Smith's five.

Chiefs (1-7) at Steelers (5-3)

6:30 p.m. Monday • ESPN • Line: Steelers by 12 1/2

• ESPN might be looking for some college hoops to put in the prime-time slot. The Chiefs have been awful in nearly every phase except running the ball. Most notable is their turnover woes: a ludicrous 29 giveaways, and a minus-20 differential. Pittsburgh has begun playing like the Steelers we expect, using a power running game, stingy defense and timely special teams. Isaac Redman and Jonathan Dwyer have 100-yard games - and they are the backups to Rashard Mendenhall.