LAS VEGAS — It looked like a mismatch even before Peyton Manning hooked up for his first touchdown pass to Wes Welker and the rest of the NFL found out just how bad the Jacksonville Jaguars really are.

But now it’s official. The Denver Broncos are the biggest favorite ever in an NFL game in this gambling city, a whopping four-touchdown pick Sunday at home against the hapless Jaguars.

And the 28-point line hasn’t stopped people from betting money on the Broncos, even after they didn’t cover the spread in Sunday’s 51-48 win over Dallas.

“It didn’t take people long to jump on the Broncos bandwagon, which is at its capacity now,” said Jay Kornegay, who runs the sports book at the LVH hotel. “And we expect that to continue.”

Betting experts say the spread surpasses the 26-point margin for favored Pittsburgh against expansion Tampa Bay in 1976.

Pink flags are out

The NFL said it won’t use its pink penalty flags in this week’s games after they caused confusion among broadcasters, fans, players and coaches Sunday.

The pink flags were part of the NFL’s “A Crucial Catch” campaign for breast cancer awareness.

Freeman set to join Vikings

EDEN PRAIRIE, Minn. — Minnesota said its quarterback this weekend will be Matt Cassel or Christian Ponder, not Josh Freeman, who the Vikings finalized a contract with Monday after he was cut by Tampa Bay. Cassel will keep the job if Ponder (ribs) is still hurt.

Freeman is set to practice today.

Extra points

• The Packers are preparing for lifte without Clay Matthews, who may be out for an extended time after breaking his right thumb during Sunday’s win over Detroit.

• From practice squad to NFL starter: QB Thad Lewis received the surprising news of his sudden promotion upon arriving at the Buffalo Bills facility Monday.

• The Oakland Raiders released quarterback Matt Flynn on Monday, just six months after bringing him in to be the starter.

• Panthers receiver Steve Smith is still upset with the officiating in Carolina’s 22-6 loss at Arizona, calling umpire Dan Ferrell “garbage.” On one play, Smith was called for offensive interference.