GLENDALE — A sluggish start staggered the Arizona Cardinals. An inability to run the ball or keep defenders off their quarterback finished them off.

Carson Palmer was sacked seven times, and the Cardinals had almost no run game to take the pressure off him, killing their chances of a comeback in a 34-22 loss to the Seattle Seahawks on Thursday night.

“We’ve got to figure out ways to start faster, both sides of the ball,” Cardinals coach Bruce Arians said. “We came out sluggish. No excuses playing on a Thursday Night Football and all that crap. We didn’t break a sweat all week, so we should have been fresh, and we didn’t play at the speed of the game that they played at the start of the game.”

Arians talked to his players during the short week about getting off to a good start against the NFC West-leading Seahawks (6-1).

They didn’t do it. Didn’t really come close, either.

Arizona’s offense stumbled in its first few drives, a stretch that included Palmer’s first interception on a deflected pass.

The Cardinals’ defense, the strong part of the team so far this season, had all kinds of trouble with Seattle’s offense, giving up a pair of touchdown passes by Russell Wilson to trail 14-0 early in the second quarter.

Arizona (3-4) managed to claw within 17-10 by halftime, thanks to a sack and a fumble recovery by the defense deep in Seattle’s end, but couldn’t keep the momentum going.

The Cardinals’ offense continued to labor until a late drive in the fourth quarter, giving up a season-high in sacks while generating 30 yards on 18 carries. Arizona finished with 234 total yards.

“Obviously, it was not our best,” Arians said. “The last few drives were OK in the 2-minute catch-up, but you have to run the football with some amount of success and we didn’t get that done.”

Palmer finished with 258 yards on 30-of-45 passing, but had two interceptions and padded his numbers in a couple of fourth-quarter drives with Seattle’s defense backing off, including an 8-yard touchdown pass to Jaron Brown.

Palmer’s first interception was on a breakup by Brandon Browner that Earl Thomas snagged, but his second came when Browner stepped in front of Michael Floyd and returned the pick 49 yards to Arizona’s 1. That set up Marshawn Lynch’s 2-yard touchdown run that put the Seahawks up 31-13 and the game all but out of reach.

Palmer has 13 interceptions this season, 11 over the past five games.

“Everybody needs to step up their game, mainly me being the quarterback — that’s your job,” Palmer said. “We’ve got to keep growing. Not enough things got better, obviously.”

Wilson finished 18 of 29 for 235 yards and three touchdowns in the stadium where he lost in his NFL debut last season. Lynch finished with 91 yards on 21 carries to give the Seahawks a nice balance.

“This was a really cool night for our football team,” said Seattle coach Pete Carroll. “We wanted to get on the road and get this thing done and continue to feel good about our ability to win on the road.”