DENVER - The best start in NHL history is over. The Chicago Blackhawks finally left the ice without a point.

The Blackhawks were stunned 6-2 by the struggling Colorado Avalanche on Friday night. It was their first loss in regulation and ended a remarkable run in which they earned at least one point in their first 24 games, an NHL record.

Matt Duchene scored four points and Ryan O'Reilly got his first goal since his contract dispute was resolved more than a week ago. O'Reilly assisted on another goal in a four-goal onslaught in the second period that turned a 1-1 tie into a laugher.

The Blackhawks (21-1-3) hadn't lost in regulation since a 6-1 rout by Nashville on March 25, 2012, and their last loss in regulation on the road came more than a year ago, with a 5-1 defeat at St. Louis on March 6, 2012.

Chicago's overall points streak was the second longest in NHL history. The 1979-80 Philadelphia Flyers set the league record with a staggering 35-game unbeaten streak that included 25 wins and 10 ties.

• Senators 3, Rangers 2: In New York, Jakob Silfverberg broke a tie with 4:41 left, and Ottawa snapped a four-game losing streak.

• Jets 3, Panthers 2, OT: In Sunrise, Fla., Dustin Byfuglien scored with 40.5 seconds left in overtime for Winnipeg. Byfuglien brought the puck across to the right circle and his wrist shot whistled past Jacob Markstrom.

• Predators 6, Oilers 0: In Nashville, Tenn., Colin Wilson had a career-high two goals and two assists, and the Predators snapped a three-game skid.