Border agents seized drugs, estimated at a combined value of $357,000, in Nogales over the weekend, officials say.

Border agents seized fentanyl, heroin, and methamphetamine at the Nogales border crossing last weekend, officials say.

On Friday, the vehicle of a 39-year-old Cuban national was referred for further inspection, according to a news release from U.S. Customs and Border Protection. A drug dog alerted to a scent during a search of the man's car, and agents found more than 61 pounds of meth and a package of fentanyl, estimated at a combined value of $185,000.

The following day, in a separate incident, officers referred the vehicle of a 21-year-old woman, a U.S. citizen, for further inspection. During the search of her vehicle, a drug dog alerted officers to the vehicle's rear quarter panels. Officers found more than 40 pounds of heroin and meth, worth an estimated $172,000, the release shows.

The vehicles and drugs were seized, the release says.

Contact reporter Gloria Knott at gknott@tucson.com or 573-4235. On Twitter: @gloriaeknott