WEST PALM BEACH, Fla. — Unable to legally bring a supplement into the U.S. to make their horses more resilient, a Venezuelan polo team used another way to get ready for a champion match: Have a pharmacy mix up the concoction.
What happened next, though, was disastrous. The chemicals were mixed wrong, and 21 horses given the brew died in rapid succession, some collapsing just before taking the field in a championship polo match. The others fell soon after, one by one, shocking a well-heeled crowd gathered to watch the U.S. Open at the International Polo Club Palm Beach in Wellington.
The Lechuza polo team had hoped to get a compound similar to a name-brand supplement used safely around the world to help horses with exhaustion but hasn't been approved by the Food and Drug Administration. Veterinarians commonly turn to compounding pharmacies for medications that can't be found on shelves, but the dispensaries can only re-create unapproved drugs in limited circumstances.
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A Florida pharmacy that mixed the medication said Thursday that an internal review found "the strength of an ingredient in the medication was incorrect." Jennifer Beckett, chief operating officer for Franck's Pharmacy in Ocala would not say whether the incorrect amount was specified in the order that came from a Florida veterinarian.
Lechuza said the order was for a compound similar to Biodyl, a supplement that includes vitamins and minerals. The team has been using the supplement for many years without problems, but typically uses the manufactured version instead of going to compounding pharmacies.
"Only horses treated with the compound became sick and died within three hours of treatment," Lechuza said in a statement. "Other horses that were not treated remain healthy and normal."
While Biodyl isn't approved in the U.S., the supplement made in France by Duluth, Ga.-based animal pharmaceutical firm Merial Ltd. is widely used abroad. The president of the Argentine Equine Veterinarian Association, Fernando Ruiz, said the supplement is commonly used on horses that compete there, and he's not aware of any deaths.
It wasn't clear how closely Franck's mixture came to the name-brand drug, though. Lechuza said what they ordered was supposed to contain vitamin B, potassium, magnesium and selenium, a mineral that can be toxic in high doses.

