WASHINGTON — The United States will be "out of Iran pretty quickly" and could return for "spot hits" if needed, President Donald Trump told Reuters on Wednesday, hours before he was scheduled to make a primetime address to the nation about the war.
With the conflict in its fifth week and Trump under pressure for an off-ramp amid rising gasoline prices, the president scheduled a 9 p.m. EDT speech to discuss the way forward. His address will end a day that began with his historic visit to the Supreme Court.
Trump, in a phone interview with Reuters, said one element of his speech would be to express his disgust with NATO for what he considers the alliance's lack of support for U.S. objectives in Iran.
U.S. President Donald Trump speaks Tuesday in the Oval Office of the White House in Washington, D.C.
A transatlantic rift in Trump's second term deepened after European allies rebuffed his request to help maintain safe passage for oil traffic through the Strait of Hormuz.
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The Republican president said he "absolutely" was considering withdrawing the United States from NATO, a treaty organization ratified by the U.S. Senate in 1949. He flirted with a withdrawal in the past and successfully pressured NATO members to increase their defense spending.
"They haven't been friends when we needed them," he said. "We've never asked them for much … it's a one-way street."
Trump and his top officials offered a variety of timelines for ending the war. He said Tuesday that the U.S. could ​end its military campaign against Iran within ‌two to three weeks.
In the Reuters interview, he declined to provide a timeline.
"I can't tell you exactly … we're going to be out pretty quickly," he said, adding that "we'll come back to do spot hits" on Iranian targets as needed.
People attend a funeral ceremony Wednesday in Tehran, Iran, for the Revolutionary Guard's Navy Commander Alireza Tangsiri, who was killed in strikes amid the U.S.-Israeli conflict with Iran.
'We got regime change'
The war spread across the Middle East, killing thousands of people and causing soaring energy prices that fueled global inflation fears.
Two-thirds of Americans believe the U.S. should work to end its involvement in the Iran war quickly, even if that means not achieving the Trump administration's goals, a Reuters/Ipsos poll conducted from Friday to Sunday found.
Trump said he hoped for a deal with Iran after the first wave of airstrikes killed Supreme Leader Ayatollah Ali Khamenei. A number of other senior Iranian figures also were killed.
Mojtaba Khamenei replaced his father as Iran's supreme leader; the U.S. said it believes he was wounded and likely disfigured. The country's president and foreign minister remain the same as before the conflict.
A member of a police force wears a badge with a picture of the late Supreme Leader of Iran, Ayatollah Ali Khamenei, as he stands guard on a street Wednesday in Tehran, Iran.
Trump said Iran's leadership was now "totally different people."
"I didn't need regime change, but we got it because of the casualties of war. We got it. So we have regime change and the big thing we have is they're not going to have a nuclear weapon," Trump said, adding, "Nor do they want one."
The White House said behind-the-scenes negotiations are ongoing with Iran, which Tehran denies. A source briefed on the matter said Vice President JD Vance talked to intermediaries from Pakistan about the conflict as recently as Tuesday.
At Trump's direction, Vance signaled privately that Trump was open to a ceasefire as long as certain U.S. demands are met, the source told Reuters on Wednesday.
"We have had full regime change," Trump said. "I'm dealing with a very good chance that we'll make a deal because they don't want to be blasted anymore."
A member of a police force stands guard on a street Wednesday in Tehran, Iran.
Nuclear weapons
Trump said a primary aim of launching the war was to prevent Iran from developing a nuclear weapon.
Almost half of Iran's uranium enriched to up to 60% purity, a short step from weapons-grade, was stored in a tunnel complex at Isfahan and is probably still there, the U.N. nuclear watchdog chief Rafael Grossi said.
The tunnel complex is the only target that appears not to have been badly damaged in attacks last June by Israel and the U.S. on Iran's nuclear facilities.
Trump said the objective of preventing a nuclear weapon was achieved. Of the enriched uranium, he said: "That's so far underground, I don't care about that."
"We'll always be watching it by satellite," he added.
He said Iran was "incapable" of developing a weapon now.
Iran long denied wanting to develop a nuclear weapon and says its nuclear program is peaceful.
The International Atomic Energy Agency estimates that when Israel launched its first attacks in June, Iran had 440.9 kg of 60% uranium. If enriched further, that would provide the explosive needed for 10 nuclear weapons, according to an IAEA yardstick.
Photos from the Mideast as Iran war continues
A man takes cover as air raid sirens sound, warning of rockets launched from Lebanon toward Israel, in Kiryat Shmona, northern Israel, Monday, March 23, 2026. (AP Photo/Ariel Schalit)
Israeli security forces and rescue team respond at the site of an Iranian missile strike in Tel Aviv, Israel, Tuesday, March 24, 2026. (AP Photo/Ohad Zwigenberg)
Relatives grieve in Baghdad, Iraq, Tuesday, March 24, 2026, during a funeral of members of the Popular Mobilization Forces who were killed in a U.S. airstrike in Anbar, Iraq. (AP Photo/Hadi Mizban)
Israeli soldiers secure the site where an Iranian missile wreckage landed in the West Bank village of Kifl Haris Tuesday, March 24, 2026. (AP Photo/Majdi Mohammed)
An Israeli soldier jumps from a tank in northern Israel near the border with Lebanon, Saturday, March 21, 2026. (AP Photo/Ariel Schalit)
Israeli security forces and rescue teams work at the site struck by an Iranian missile in Arad, southern Israel, Sunday, March 22, 2026. (AP Photo/Ohad Zwigenberg)
Israeli security forces survey the site that was struck by an Iranian missile in Dimona, southern Israel, Sunday, March 22, 2026. (AP Photo/Ariel Schalit)
Smoke and flames rise from an Israeli airstrike that hit the Qasmiyeh Bridge near the coastal city of Tyre, Lebanon, Sunday, March 22, 2026. (AP Photo/Mohammad Zaatari)
Rescue workers and first responders work at a residential building hit in an earlier U.S.-Israeli strike in Tehran, Iran, Monday, March 23, 2026. (AP Photo/Vahid Salemi)
Children play beside a fragment of an Iranian ballistic missile that landed in a schoolyard in the Israeli settlement of Peduel in the West Bank Monday, March 23, 2026. (AP Photo/Ohad Zwigenberg)
People follow a truck carrying the flag draped coffins of Gen. Ali Mohammad Naeini, a spokesperson for Iran’s paramilitary Revolutionary Guard and one of his comrades Amir Hossein Bidi , during their funeral procession in Tehran, Iran, Saturday, March 21, 2026. (AP Photo/Vahid Salemi)
Iranian worshippers perform Eid al-Fitr prayers marking the end of the holy fasting month of Ramadan as one of them wears an Iranian flag at the Imam Khomeini Grand Mosque in Tehran, Iran, Saturday, March 21, 2026. (AP Photo/Vahid Salemi)
A displaced woman who fled Israeli airstrikes in southern Lebanon, carries her belonging as she moves to a better spot to shelter from the rain, past an Arabic anti-war poster that reads, "Sacrificing for whom? Lebanon does not need war," in Beirut, Saturday, March 21, 2026.(AP Photo/Hussein Malla)
Iranian Kurdish Mariam crosses the Haji Omeran border crossing on foot between Iran and the autonomous Kurdistan Region of Iraq (KRI), Iraq, Sunday, March 15, 2026, as the border remains open. (AP Photo/Leo Correa)
A man cleans debris from his apartment damaged when a nearby police station was hit Friday in a U.S.-Israeli strike in Tehran, Iran, Sunday, March 15, 2026. (AP Photo/Vahid Salemi)
The shattered structure of a police station is seen after it was hit Friday in a U.S.-Israeli strike in Tehran, Iran, Sunday, March 15, 2026. (AP Photo/Vahid Salemi)
A FlyDubai plane is parked at Dubai International Airport as smoke rises in the background after a drone struck a fuel tank early morning, forcing the temporary suspension of flights, in Dubai, United Arab Emirates, Monday, March 16, 2026. (AP Photo)
A member of the armed wing of the Kurdish-Iranian opposition group Organization of Iranian Kurdistan Struggle, known as Khabat, stands in front of a shrapnel pockmarked wall that allegedly was damaged in strike by Iranian-backed militias in Iraq last week at a military base on the outskirts of Irbil, Iraq, Monday, March 16, 2026. (AP Photo/Leo Correa)
Israeli security forces inspect a house in east Jerusalem where a fragment of an Iranian missile crashed onto the rooftop, Monday, March 16, 2026. (AP Photo/Mahmoud Illean)
Israeli soldiers operate next to their mobile artillery unit on the border with Lebanon in northern Israel, Monday, March 16, 2026. (AP Photo/Ariel Schalit)
Nofar Eliash holds her dog as she takes shelter with others while air raid sirens warn of incoming Iranian and Hezbollah missile strikes in Kiryat Shmona, northern Israel, Monday, March 16, 2026. (AP Photo/Ariel Schalit)
A man runs past a bulldozer clearing debris from a building damaged in an Israeli airstrike in Dahiyeh, Beirut's southern suburbs, Lebanon, Tuesday, March 17, 2026. (AP Photo/Hassan Ammar)
Residents inspect a house damaged yesterday by a projectiles launched from Lebanon in Nahariya, northern Israel, Tuesday, March 17, 2026. (AP Photo/Ariel Schalit)
Israeli air defense system fires to intercept missiles during an Iranian attack over Tel Aviv, Israel, early Sunday, March 15, 2026. (AP Photo/Ohad Zwigenberg)
Volunteers clean debris from a residential building damaged when a nearby police station was hit Friday in a U.S.-Israeli strike in Tehran, Iran, Sunday, March 15, 2026. (AP Photo/Vahid Salemi)
People walk past tents sheltering people displaced by Israeli airstrikes at a public space along the Beirut waterfront at sunset in Beirut, Lebanon, Sunday, March 15, 2026. (AP Photo/Hassan Ammar)
Fire and plumes of smoke rise after a drone struck a fuel tank forcing the temporary suspension of flights. near Dubai International Airport, in United Arab Emirates, early Monday, March 16, 2026. (AP Photo)

